AAEP Guidelines for Serology in Horses with Adverse Events from Vaccination

These guidelines are intended to be a reference for veterinarians who wish to utilize serological testing to determine levels of circulating antibodies (titers) to specific pathogens.

It should be recognized that levels of circulating antibodies are only one component of a complex immune system and that for most vaccine antigens the correlation between serological response to vaccination and protection in the horse has not been well established. As such, obtaining and assessing levels of circulating antibodies to specific pathogens has limitations.