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Equine Protozoal Myeloencephalitis (EPM)

Equine protozoal myeloencephalitis (EPM) is a neurologic disease of horses caused by protozoal infection of the central nervous system. Sarcocystis neurona causes most cases; Neospora hughesi can also cause disease. Both organisms are obligate intracellular pathogens in the protozoan phylum Apicomplexa.